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Efflux Pump Regulation and Intrinsic Resistance in Soil-Derived Bacterial Isolates

Agricultural Microbiology

Antibiotic Resistance Determinants in Environmental Bacteria

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Agricultural Microbiology › Antibiotic Resistance Determinants in Environmental Bacteria

Efflux Pump Regulation and Intrinsic Resistance in Soil-Derived Bacterial Isolates

This research characterizes the genomic architecture and regulatory mechanisms controlling multidrug efflux pump expression in naturally occurring agricultural soil bacteria through transcriptomic and proteomic approaches. The discoveries elucidate how intrinsic resistance mechanisms confer broad-spectrum protection and facilitate subsequent acquired resistance accumulation.

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