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Metagenomics-Based Functional Annotation of Uncultured Xenobiotic-Degrading Microorganisms

Agricultural Microbiology

Microbial Degradation of Agricultural Xenobiotics

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Enzymatic Degradation Pathways of Synthetic Pesticide Metabolites Horizontal Gene Transfer Networks in Herbicide-Resistant Microbial Communities Co-metabolic Degradation of Complex Fungicide Compound Mixtures Genomic and Transcriptomic Analysis of Novel Xenobiotic-Degrading Bacterial Isolates Fungal Ligninolytic Enzyme Systems for Persistent Organic Pollutant Mineralization Soil Microhabitat Physicochemistry Regulating Xenobiotic Biodegradation Kinetics Protein Engineering and Directed Evolution of Xenobiotic-Degrading Enzymes Quorum Sensing and Biofilm Formation Regulating Cooperative Xenobiotic Catabolism Systems-Level Modeling of Pesticide-Microbiome Interactions and Metabolic Flux

Agricultural Microbiology › Microbial Degradation of Agricultural Xenobiotics

Metagenomics-Based Functional Annotation of Uncultured Xenobiotic-Degrading Microorganisms

This research uses shotgun metagenomics and functional metatranscriptomics to identify and characterize novel degradative genes and enzymatic activities from unculturable environmental microbes participating in pesticide mineralization. The discovery of cryptic metabolic pathways expands the catalogue of biocatalytic mechanisms and enables synthetic biology approaches for bioaugmentation applications.

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