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Metabolomic Profiling of Efflux Pump-Mediated Fungicide Tolerance

Agriculture Plant Pathology

Fungicide Resistance Monitoring Programs

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Agriculture Plant Pathology › Fungicide Resistance Monitoring Programs

Metabolomic Profiling of Efflux Pump-Mediated Fungicide Tolerance

This research employs untargeted and targeted metabolomics to characterize metabolic reprogramming in efflux pump-overexpressing resistant isolates and identify biomarker metabolites associated with transporter-mediated resistance. The study reveals metabolic signatures enabling non-invasive detection of resistance phenotypes and identifies potential metabolic vulnerabilities for resistance management.

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