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Golgi Apparatus Stacking and Trans-Golgi Network Organization

Molecular Biology
Organelle Biogenesis Molecular Mechanism Study
Golgi Apparatus Stacking and Trans-Golgi Network Organization
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Molecular BiologyOrganelle Biogenesis Molecular Mechanism Study

Golgi Apparatus Stacking and Trans-Golgi Network Organization

Students will investigate the molecular mechanisms maintaining Golgi cisternae architecture through studying tethering complexes (COG, GARP), membrane trafficking dynamics, and glycosylation enzyme localization. Research will involve super-resolution microscopy, biochemical reconstitution assays, and live-cell imaging to elucidate how organellar organization relates to cargo sorting and protein modification.

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