Comparative Genomic Analysis Across Cancer Types and Populations

Clinical Medical Bioinformatics › Cancer Genomics Mutation Signature Analysis

Comparative Genomic Analysis Across Cancer Types and Populations

Interns will conduct comparative analyses of mutational signature profiles across different cancer types, tumor subtypes, and diverse patient populations to identify pan-cancer patterns and population-specific variations. They will work with large-scale genomic datasets to determine conservation and divergence of signatures, investigating factors like ancestry, genetic background, and exposure that influence signature distributions. This includes implementation of visualization and statistical frameworks for multi-cohort analysis.

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