Somatic Mutation Pattern Recognition in Tumor Genomes

Clinical Medical Bioinformatics › Cancer Genomics Mutation Signature Analysis

Somatic Mutation Pattern Recognition in Tumor Genomes

Interns will analyze whole-genome and exome sequencing data to identify and characterize recurrent somatic mutation patterns across different cancer types. They will learn to use bioinformatics tools to detect single nucleotide variants (SNVs), insertions/deletions, and structural variants that define cancer-specific genomic landscapes. This work involves data preprocessing, variant calling, and annotation using established pipelines and databases.

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