Etiology Attribution and Carcinogenic Process Inference

Clinical Medical Bioinformatics › Cancer Genomics Mutation Signature Analysis

Etiology Attribution and Carcinogenic Process Inference

Interns will investigate the biological and environmental processes driving cancer development by correlating identified mutational signatures with known carcinogens and DNA damage mechanisms. They will conduct literature-based analysis and contribute to mechanistic studies that link signature patterns to exposure histories, defective DNA repair pathways, and oncogenic processes. This includes statistical association studies and interpretation of signature contribution levels in patient samples.

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